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Sunday, October 29, 2017

Case Study and Case Report. 2017; 7(4): 95 - 100.

Mistro P, Gomes ROphiasis following Zika virus infection: a case report. Case Study Case Rep. 2017; 7(4): 95 - 100.

ABSTRACT

Zika virus infection is an important public health issue at present. The trichological manifestation of Zika virus infection is little mentioned in the literature. Here, the authors report a case presenting with ophiasis following Zika virus infection. According to our best knowledge, this is the first report on this problem.


Key words:  Ophiasis, Zika, infection

Case Study and Case Report. 2017; 7(4): 91 - 94.

Zhang J, Shi SL. Hot cross bun sign in a patient with CADASIL: a case report. Case Study Case Rep. 2017; 7(4): 91 - 94.

ABSTRACT

Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) is an inherited arteriopathy whose key features include migraine headaches, recurrent subcortical ischaemic events and vascular dementia. Here, we report on a patient with the hot cross bun sign who presented with CADASIL.

Key words:  Hot cross bun sign, CADASIL, MSA


Thursday, October 5, 2017

Case Study and Case Report. 2017; 7(4): 88 - 90.

Prasad R, Prasad M. Tongue bee sting and severe allergy after drinking soft drink contaminated with bees. Case Study Case Rep. 2017; 7(4): 88 - 90.

ABSTRACT

Dengue is a common problem in tropical medicine. This infection can manifest as acute febrile illness and might result in hemorrhagic complication. Long term complication due to dengue is rarely mentioned. The hepatic dysfunction due to dengue is observable and the problem can last for a long term. In this case report, the authors report on an interesting case of post dengue elevation of serum transaminase. The long term follow-up of the case until returning to normal limit was done. The period that requires for returning to normal is 8 months. The elevation of serum transaminase enzymes after acute dengue infection is possible and it can spontaneous resolve without any requirement for specific management. Nevertheless, the time required for returning to normal is long. Based on our best knowledge, this is the first world report on the closed follow-up of case with post dengue elevation of serum transaminase.


Key words:  Bee, tongue, sting

Tuesday, September 26, 2017

Case Study and Case Report. 2017; 7(4): 83 - 87.

Prasad S, Prasad T, Amerva T. Post - dengue elevation of serum transaminase until returning to normal limit: long term follow-up. Case Study Case Rep. 2017; 7(4): 83 - 87.

ABSTRACT

Dengue is a common problem in tropical medicine. This infection can manifest as acute febrile illness and might result in hemorrhagic complication. Long term complication due to dengue is rarely mentioned. The hepatic dysfunction due to dengue is observable and the problem can last for a long term. In this case report, the authors report on an interesting case of post dengue elevation of serum transaminase. The long term follow-up of the case until returning to normal limit was done. The period that requires for returning to normal is 8 months. The elevation of serum transaminase enzymes after acute dengue infection is possible and it can spontaneous resolve without any requirement for specific management. Nevertheless, the time required for returning to normal is long. Based on our best knowledge, this is the first world report on the closed follow-up of case with post dengue elevation of serum transaminase.

Key words:  Dengue, transaminase


Wednesday, August 16, 2017

Case Study and Case Report 2017; 7(3): 76 - 82.

Yunus M, Purwahidayat A, Srianto P, Mufasirin, Legowo D, Ferdiansyah H. Analysis of the
cause of Cetacean “short-finned pilot whales (Globicephala macrorhynchus)” strandings on
Probolinggo Coast, East Java Province, Indonesia. Case Study Case Rep. 2017; 7(3): 76 - 82.

ABSTRACT
Indonesian waters is one of the habitat and simultaneously a migration path so many different
species of mammals of Cetacean (whales and dolphins) and Sirenia. Whales and dolphins are
a group of aquatic animals that are often washed up on the shores of Indonesia. Strandings of
marine mammals requires fast action and precise handling, particularly those that are still
alive so it can be saved, as a safeguard and preservation. The researchers do not have a
definitive reason why stranded marine mammals, but there are many theories and analytical
approach through the predictions are used to determine the cause. The social life of animals,
bad weather, extreme ocean waves and animals follow prey to the beach are some of the most
likely causes. Some of the other causes that have been identified is a disease, a parasitic
infection, the growth of harmful algae, injuries from boat collisions or entangled, trauma,
hunger and military exercises using special sonar. The current of the tides are strong and vary
from day to day, causing indeterminate conditions for navigation are predicted as one of the
causes. Decreased oxygen levels and water salinity are thought to be among the causes that
led dozens of short-finned pilot whales to wash up on a beach in Randupitu village, Gending
district, Probolinggo regency, East Java. Data from the Meteorology, Climatology and
Geophysics Agency (BMKG) Juanda, Surabaya, reveals that it was likely that strong currents
in the northern Java Sea had carried the pilot whales ashore. According to the data, strong
winds of more than 28 knots caused high seas with 2 to 3.5 meter waves. The high waves also
caused oxygen level decreases deep below the surface and lowered water salinity, which was
accompanied with a sea level rise. The BMKG added that these three elements had led deep
water fish to migrate to the surface, leading many of them to become stuck in shallow waters.

Keywords: Pilot whales, analysis, cause, stranding

Tuesday, July 18, 2017

Case Study and Case Report 2017; 7(3): 65 - 75.

Salmanoglu E, Kurutas EB. Effects of 99mTc-MDP bone scintigraphy on
oxidative/nitrosative stress biomarkers in patients. Case Study Case Rep. 2017; 7(3): 65 - 75

ABSTRACT
We aimed to define the effects of Technetium-99m Methylendiphosphonate bone
scintigraphy on oxidative/nitrosative stress in patients after intravenous injection and
compared to healthy control group. Forty patients for bone scintigraphy and forty healthy
control group were included this study. The age range was similar in both groups (18-74
years). The blood samples were taken from patients 2 hour after intravenous injection of 20
mCi (740 MBq) Technetium-99m Methylendiphosphonate. The activities of catalase,
superoxide dismutase and malondialdeyhde levels were measured as oxidative stress
biomarkers and nitric oxide and nitrotyrosine levels were measured as nitrosative stress
biomarkers in patients and control group. There were no significant differences according to
both age and sex between two groups (p˃0.05). Activities of catalase and superoxide
enzymes and malondialdeyhde levels in patients were increased in patients compared to
controls (p<0.05). Also, nitric oxide and nitrotyrosine levels in patients were higher than
control group (p<0.05). Technetium-99m Methylendiphosphonate may cause both oxidative
and nitrosative stress in patients. Also antioxidant defense of the patients was higher
compared to healthy subjects possibly due to a compensatory response to ionising radiation in
the living cells and thereby protects the cells against oxidative/nitrosative damage.
Keywords: Bone scintigraphy, oxidative/nitrosative stress, catalase, superoxide dismutase,
malondialdehyde, nitric oxide, nitrotyrosine

Saturday, July 8, 2017

Case Study and Case Report 2017; 7(3): 53 - 64.

Mól N, Ptak K, Zasada M, Końska K, Pilch M, Knapp A, Kwinta P. Hunter Syndrome complicated by a communicating hydrocephalus and arachnoid cysts at a very young age. Case Study Case Rep. 2017; 7(3): 53 - 64.

ABSTRACT

Mucopolysaccharidosis type II (MPS II) is an X-linked recessive lysosomal storage disease caused by deficient activity of iduronate 2-sulfatase, which regulates  lysosomal catabolism of the glycosaminoglycans. As a consequence, undegraded dermatan and heparan sulfates accumulate in all the tissues and organs of the body, including the central nervous system, where they cause irreversible changes. Some of the neurological manifestations include behavioral problems, mental retardation or cognitive deterioration, ventriculomegaly, hydrocephalus, compressive myelopathy, seizures or hearing loss. This report describes an infant boy diagnosed with MPS II who presented with an acute communicating hydrocephalus and arachnoid cysts at 9 months of age. The patient was diagnosed with MPS II shortly after birth because of his positive family history. At that time he did not present any physical manifestation of the disease, all the imaging studies of the head, abdomen and cardiac function were normal. He was started on enzyme replacement therapy with Elaprase®, which he received every week at our Clinic. Such frequent visits allowed for an immediate diagnosis of sudden increase of the intracranial pressure and the timely surgical intervention. To the best of our knowledge, this is the first reported case of a patient with MPS II, who developed acute hydrocephalus requiring surgical implementation of a ventriculo-peritoneal shunt at such a young age.

Keywords: Hunter Syndrome, hydrocephalus, arachnoid cyst