Case Study and Case Report 2024; 14(3): 19 - 22.

Sant K, Sant R. Abnormal Urine Color Due to Consumption of Locally Made Herbal Regimen: A Case Report. Case Study and Case Report 2024; 14(3): 19 - 22. ABSTRACT Herbal remedies are commonly used worldwide for their perceived health benefits, particularly in traditional medicine. However, their consumption can sometimes lead to unexpected adverse effects, including changes in urine color. We present the case of a 45-year-old female who developed dark-colored urine after consuming a locally made herbal regimen. The patient reported drinking a concoction of various herbs purchased from a local market, following recommendations for improving general health. Upon examination, her urine was found to be dark brown, with no history of hematuria or associated pain. Laboratory investigations, including a urinalysis, revealed myoglobinuria, suggesting that muscle damage was the cause of the discolored urine. Further investigations revealed that the herbal regimen contained St. John's Wort, a herb known to potentially cause rhabdomyolysis in some individuals. After discontinuing the herbal regimen and receiving supportive care, the patient’s urine color normalized, and her muscle enzymes returned to baseline. This case highlights the potential dangers of unregulated herbal medicines, especially those with unknown ingredients and unmonitored production practices. Health practitioners should be cautious about advising or prescribing such treatments without awareness of their possible side effects. Keywords: Herbal regimen, Abnormal urine color, Myoglobinuria, Rhabdomyolysis, St. John's Wort