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Monday, June 3, 2024

Case Study and Case Report 2024; 14(1): 6 – 8.

Buala D. Uncovering Hidden Conflicts of Interest in Published Articles: The Case of COVID-19 Vaccine Recommendations. Case Study and Case Report 2024; 14(1): 6 – 8. ABSTRACT This article examines the issue of conflicts of interest in published articles. The new sort of conflict of interest in today's extensively used social media environment is something fresh to be noticed. The highlighted case, “Lataster” case, is a problematic case published in a clinical assessment publication by a non-MD author who authored and suggested/recommended the use of COVID-19 vaccine. This author has a hidden non-disclosed conflict of interest a business owner of a website blog that exposes anti-COVID-19 vaccination reactions. Keywords: Conflict of interest, journal, publication, ethic

Saturday, June 1, 2024

Case Study and Case Report 2024; 14(1): 3 - 4.

Sran D. Gastrointestinal bleeding due to enteric fever. Case Study and Case Report 2024; 14(1): 3 - 5. ABSTRACT Enteric fever, caused by Salmonella enterica serovar typhi and Salmonella enterica serovar paratyphi, is a systemic bacterial infection. Symptoms include fever, headache, malaise, changes in bowel habits, and abdominal pain. Blood culture is typically used to diagnose the infection. Complications can include gastrointestinal issues such as bleeding and perforation. In this case, a 33-year-old male presented with lower gastrointestinal bleeding as a complication of enteric fever. He was treated with antibiotics and other medications, and ultimately recovered well. Enteric fever is a significant public health concern in developing countries, and early treatment is essential to prevent complications. Keywords: enteric fever, gastrointestinal, bleeding

Monday, May 27, 2024

Case Study and Case Report 2024; 14(1): 1 – 2.

Dungsupawong H. Ethical dilemma in the journal retraction process. Case Study and Case Report 2024; 14(1): 1 – 2. ABSTRACT This abstract discusses the retraction of an article in the journal J Eval Clin Pract, highlighting concerns about ethics and communication within the editorial team. The retraction process was initiated without prior communication from the Editor in Chief, raising questions about transparency and accountability. The article in question was a comment that passed standard review and had no ethical violations, but was retracted due to pressure from the publisher related to the primary author's behavior on social media. The primary article being criticized had its own ethical issues, yet no action was taken against it. This suggests a lack of fairness in the retraction process and calls for greater transparency and consistency moving forward. The focus should be on addressing ethical issues in published articles rather than targeting authors for engaging in social media discussions. Key words: ethic, dilemma, retraction, process

Case Study and Case Report 2023; 13(4): 40 – 43.

Dungsupawong H. Ethical dilemma in the journal retraction process. Case Study and Case Report 2024; 14(1): 1 – 2. ABSTRACT This abstract discusses the retraction of an article in the journal J Eval Clin Pract, highlighting concerns about ethics and communication within the editorial team. The retraction process was initiated without prior communication from the Editor in Chief, raising questions about transparency and accountability. The article in question was a comment that passed standard review and had no ethical violations, but was retracted due to pressure from the publisher related to the primary author's behavior on social media. The primary article being criticized had its own ethical issues, yet no action was taken against it. This suggests a lack of fairness in the retraction process and calls for greater transparency and consistency moving forward. The focus should be on addressing ethical issues in published articles rather than targeting authors for engaging in social media discussions." Key words: ethic, dilemma, retraction, process

Friday, December 22, 2023

Case Study and Case Report 2023; 13(4): 40 – 43.

Domeer S, Purine Q. Coexistence of sodium and chloride channelopathies: A complex phenotype with features of myotonia congenita and paramyotonia congenita. Case Study and Case Report 2023; 13(4): 40 - 43. Non-dystrophic myotonias (NDM) encompass chloride and sodium channelopathy disorders. This case study presents a 34-year-old female patient with a complex phenotype involving features of both myotonia congenita (MC) and paramyotonia congenita (PMC). Initially presenting with asthenia, weakness, and limb stiffness in her second decade of life, her symptoms gradually worsened over time. She experienced frequent retrosternal compression, tachycardia, stiffness, and symmetrical pain in her lower limbs. Clinical examination and electromyography confirmed severe lid lag myotonia, hypertrophy in all four limbs, and myotonic discharges. Exposure to cold triggered her symptoms, significantly impacting her daily life. Initial treatment with mexiletine was switched to acetazolamide due to gastrointestinal side effects. Genetic analysis revealed a new variant, p.Glu1607del, in SCN4A and homozygosity for p.Met485Val in CLCN1. This case underscores the importance of accurate diagnosis and appropriate therapy guided by an expert neurologist. Keywords: myotonia, paramyotonia, channelopathies, CLCN1, SCN4A

Thursday, November 9, 2023

Case Study and Case Report 2023; 13(4): 35 – 39.

Demir S, Yurab R. CASTLE Thyroid Tumor: A Case Report. Case Study and Case Report 2023; 13(4): 35 – 39. ABSTRACT A rare tumor of the thyroid gland, known as thymus-like differentiated carcinoma, bears structural resemblance to thymic tissue. The prognosis for this type of tumor is generally positive. While radiotherapy has proven effective as a localized treatment, instances of distant recurrence have been reported. In order to lower the risk of recurrence, it has been recommended to incorporate chemotherapy into the treatment regimen. In this case report, we present the successful treatment of a patient with a large tumor and extrathyroidal extension. The patient received surgery, radiotherapy, and cisplatin, which resulted in manageable side effects. Three years later, the patient remains disease-free both locally and in distant sites. Key words: CASTLE, thyroid, tumor

Case Study and Case Report 2023; 13(3): 31 - 34.

Dashtseren Y, Ranishen P. Aspergilloma-Replicating Lung Cancer: A Case Study. Case Study and Case Report 2023; 13(3): 31 - 34. ABSTRACT Aspergilloma is a formation consisting of Aspergillus hyphae, fibrin, mucus, and cellular debris found in a lung cavity or dilated bronchus. Computerized tomography (CT) scans often show a cavity with a solid mass and a crescent sign, which are characteristic of aspergillomas. However, the European Respiratory Society advocates for a more comprehensive diagnostic approach. This case report describes a patient initially diagnosed with an aspergilloma based on CT findings, presenting with a cavitary lesion and intracavitary lobular opacity in the left upper lobe, along with a history of hemoptysis. After resection, histological examination contradicted the initial diagnosis and revealed lung cancer. This highlights the importance of obtaining a tissue diagnosis from the beginning or using a multifaceted diagnostic approach that includes radiological findings, serology, and microbiology tests. In the absence of an initial tissue diagnosis, regular follow-up and early interval scanning Key words: Aspergilloma, lung, cancer