Case Study and Case Report 2021; 11(2): 28 - 31.

Enapo IC, Ekpepe RK. Diabetes ketoacidosis and Burgada syndrome. Case Study Case Rep. 2021; 11(2): 28 - 31. ABSTRACT Brugada syndrome is an uncommon cardiac syndrome. Burgada syndrome is characterized by cardiac arrhythmia that is associated with right bundle branch block pattern (RBBB) and ST-segment elevation in right precordial leads. It is believed to be a genetic disorder. However, non-genetic problems have also been reported as a cause of Burgada syndrome. Here, we presented a case of Brugada pattern associated with diabetic ketoacidosis (DKA). The patient is a 21 year-old-male who presented with DKA and he had clinical feature of Brugada pattern. Brugada syndrome in DKA is consistent with prevalence of this clinical disorder among male patient. Keywords: Diabetes ketoacidosis, Burgada syndrome

Case Study and Case Report 2021; 11(2): 18 - 27.

Enato IG, Akhimienho KI, Akhirevbulu ICG. Clinical features and risk factors of purple glove syndrome following intravenous administration of phenytoin in children: a case report in a Nigerian infant and review of literature. Case Study and Case Rep. 2021; 11(2): 18 - 27. ABSTRACT Several cases of purple glove syndrome (PGS) have been reported in adults and a few in children. However little or none is known about PGS in children in Africa, including Nigeria, as no known case has been reported in Nigerian children. We describe a case of PGS with compartment syndrome in a Nigerian infant; we also discuss the incidence, risk factors and complications of PGS in children. E.E is a one-year-old girl, who presented with features of severe malaria, shock and severe sepsis; and developed status epilepticus on admission. A single dose of Intravenous (IV) phenytoin was administered using a 24G cannula via one of the superficial veins on the dorsum of the left hand. Swelling of the left hand and bluish discolouration of the left thumb were noticed after 24 hours post IV phenytoin. A diagnosis of purple glove syndrome with compartment syndrome was made. Fasciotomy was performed on her hand; she recovered and was discharged after a prolonged hospital stay of two weeks. PGS can also occur in Nigerian children and it should be considered in all cases of skin discoloration and swelling at intravenous sites following administration of phenytoin. Underlying morbidities, such as severe sepsis, shock, metabolic acidosis, status epilepticus, may be major risk factors for PGS in children. Low index of suspicion by clinicians, unconsciousness and inability to localize pain may be additional risk factors in young children for development of complications such as compartment syndrome. Keywords: Purple Glove Syndrome, Phenytoin, Compartment Syndrome, Nigerian Infant. Keywords: Purple Glove Syndrome, Phenytoin, Compartment Syndrome, Nigerian, Infant

Case Study and Case Report. 2021; 11(2): 15 - 17.

Rolla FR, Mistchenbo F. Acute pancreatitis as presentation of dengue. Case Study and Case Rep. 2021; 11(2): 15 - 17. ABSTRACT Dengue is an important tropical arboviral infection. The disease can present as acute febrile disease with hemorrhagic problem. However, dengue can have atypical clinical presentation. Here, the authors present a case of acute pancreatitis as the first clinical presentation of dengue. The patient got full recovery after intensive fluid replacement therapy. Keywords: Dengue, pancreatitis, presentation

Case Study and Case Report. 2021; 11(1): 7 - 14.

Nyong EE, Idholo U, Akhimeinho KI, Akpan RJ. Perinatal Varicella in a Nigerian neonate. Case Study and Case Rep. 2021; 11(1): 7 - 14. ABSTRACT Perinatal varicella results from a DNA virus of the herpes family. It is acquired within 10days of delivery in contrast to congenital varicella whose occurrence is within the first 20 weeks of conception. Mortality is usually high where there are no modern neonatal intensive care and varicella immunoglobulin are not available. The objective of the report is to highlight the non-protective effect in neonatal varicella when infection is acquired within a particular period during pregnancy. Methods: We describe a case of a Nigerian neonate who had features of chicken pox at age of 9 days of life and was delivered by a mother who had chicken pox 4 days before the onset of labour. The neonate developed severe bronchopneumonia, a known complication, and progressively deteriorated till demise in the absence of administration of varicella immunoglobulin. In conclusion, absence of prophylactic acyclovir, delayed administration of therapeutic intravenous acyclovir, absence of administration of varicella zoster immunoglobulin, complication of sepsis and bronchopneumonia contributed to the poor prognosis. Keywords: Herpes, Immunoglobulin, Perinatal, Varicella

Case Study and Case Report. 2021; 11(1): 4 - 6.

Fernandes R. COVID-19, facemask wearing, riding and accident. Case Study and Case Rep. 2021; 11(1): 4 - 6. ABSTRACT COVID-19 is a new viral infection that results in pandemic. One of important preventive measures against COVID-19 is facemask wearing. The usefulness of facemask wearing is generally accepted. Nevertheless, the problem caused by facemask wearing is little mentioned. In this report, the author presents a case study on motorcycle accident that relating to facemask wearing riding a motorcycle. Keywords: COVID-19, facemask, accident, motorcycle

Case Study and Case Report 2021; 11(1): 1 - 3.

Fernandes I. Bloody salivary as a clinical presentation in COVID-19. Case Study and Case Rep. 2021; 11(1): 1 - 3. ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease is an important medical problem. The clinical presentation COVID-19 is various and it might sometimes be under diagnosed. Here, the author presents a case of COVID-19 patient presenting with bloody salivary. This case can highlight the importance of atypical clinical presentation of COVID-19. Keywords: COVID-19, blood saliva

Case Study and Case Report 2020; 10(4): 45 - 47.

Pranka I. Diabetic ketoacidosis precipitated by COVID-19: A report. Case Study Case Rep. 2020; 10(4): 45 - 47. ABSTRACT In clinical endocrinology, the relationship between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease (COVID-19) and diabetes mellitus is interesting. Here, the authors report on a patient with diabetes mellitus who presented to our hospital with diabetic ketoacidosis. Keywords: COVID-19, diabetes mellitus, ketoacidosis