Case Study and Case Report 2022; 12(1): 6 - 10.

Ramindo TH, Pusin Q. Aortic valve insufficiency due to myxomatous degeneration: a case report. Case Study and Case Report 202; 12(1): 6 – 10. ABSTRACT Myxomatous degeneration is a non-inflammatory degenerative disease that causes acid mucopolysaccharide accumulation in the valve's fibrosa layer. This form of degeneration most usually affects the mitral valve, resulting in mitral regurgitation; nevertheless, few cases of myxomatous aortic valve degeneration resulting in acute decompensated heart failure have been recorded. We present a case of acute decompensated heart failure caused by myxomatous aortic valve degeneration to emphasize the need of investigating myxomatous degeneration as an underlying etiology of symptomatic aortic insufficiency. Over the course of a month, a 61-year-old woman developed increasingly worsening dyspnea, cough, and peripheral edema. Aortic valve regurgitation was discovered through a clinical evaluation and imaging investigations (AVR). Following that, the aortic valve was replaced. The histology result indicated that the aortic valve had myxomatous degeneration. The patient was sent home once his symptoms improved. The bioprosthetic valve had a normal hemodynamic profile across it, with no aortic regurgitation or paravalvular leak, according to a subsequent transesophageal echocardiography. We present a case of heart failure caused by myxomatous aortic valve degeneration with a distinctive appearance. In addition, a review of the available literature on myxomatous aortic valve degeneration was undertaken to highlight the importance of early diagnosis and adequate treatment in improving the quality of life of patients. Keywords: Aortic regurgitation; valvular disease; myxomatous degeneration